Acetylcysteine, N-Acetylcysteine, NAC, Acetyl-L-Cysteine, Acetylcysteinum, 616-91-1

Acetylcysteine, N-Acetylcysteine, NAC, Acetyl-L-Cysteine, Acetylcysteinum, 616-91-1

🧪 Chemical Properties

• Chemical Name: N-Acetyl-L-Cysteine

• Molecular Formula: C₅H₉NO₃S

• CAS Number: 616-91-1

• Structure: Acetylated derivative of the amino acid L-cysteine

• Forms: Effervescent tablet, sachet (powder), ampoule (injection), oral solution

🩺 Medical Applications

⚠️ Side Effects

• Common: Nausea, vomiting, abdominal discomfort, rash, fever

• Serious: Urticaria, difficulty breathing, swelling of face/tongue/throat, bloody cough, jaundice, dark urine

• Allergic Reactions: Rare but potentially severe

💊 Dosage & Administration

Note: If vomiting occurs within 1 hour of ingestion, a repeat dose may be necessary.

🌿 Natural Sources & Supplement Form

• Naturally found in: Allium species like garlic and onion

• As a supplement: Available in NAC capsules/tablets (typically 600 mg)

🧬 Biological Effects

• Glutathione Precursor: Supports synthesis of the body’s most powerful antioxidant

• Liver Protection: Detoxifies harmful substances

• Brain Health: Studied for potential roles in depression, bipolar disorder, and addiction support

🧪 Scientific & Technical Names

• N-Acetylcysteine (full English name)

• NAC (abbreviation)

• Acetyl-L-Cysteine

• Acetylcysteinum (Latin pharmaceutical name)

💊 Brand Names (Turkey & Global)

🌍 International Names

• Fluimucil – Common in Europe

• Mucomyst – Used in the U.S. for acetaminophen overdose

• Acetadote – IV form for hospital use

✅ NAC Suitability Table

🔍 Notes

• Effervescent tablets dissolve quickly and offer high bioavailability

• Syrup form is easier for children to take

• IV form is strictly for hospital use under medical supervision

• NAC supplements are available over-the-counter but should be used cautiously for medical purposes

⚠️ Usage Precautions

1. Dosage & Instructions

• Always follow your doctor’s prescribed dose and duration

• Read the leaflet carefully; dissolve effervescent tablets in the correct amount of water

• If vomiting occurs within 1 hour, consult your doctor about repeating the dose

2. Timing

• Preferably taken after meals to reduce stomach upset

• Maintain consistent timing daily; avoid missed doses

3. Drug Interactions

• Essential to consult a doctor if using for acetaminophen overdose

• May interact with antihypertensives, antibiotics, or other medications

4. Storage Conditions

• Store in a cool, dry place away from heat and moisture

• Keep effervescent tablets sealed to prevent degradation

🚨 Application Precautions

1. Allergic Reactions

• Seek immediate help for hives, breathing difficulty, or facial swelling

• Inform your doctor if you have a sulfur allergy

2. Side Effects

• Common: nausea, vomiting, rash, fever

• Serious: bloody cough, jaundice, dark urine, loss of appetite

3. Use in Children

• Syrup or low-dose sachets preferred

• Not recommended for children under 2 without medical supervision

4. Nebulizer Use

• Ensure proper cleaning and dosage calibration of the device

• Sterilize after each use to prevent contamination

Disclaimer: This guide is for informational purposes only. Always consult a healthcare professional before using any medication or supplement.