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Send EmailHydroxypropyl Cellulose, HPC, Hypromellose, 9004-64-2
Hydroxypropyl Cellulose (HPC)
General Information
| Property | Value |
|---|---|
| CAS No. | 9004-64-2 |
| Chemical Name | Hydroxypropyl Cellulose |
| Molecular Formula | C3H7O* |
| Molecular Weight | 59.08708 g/mol |
| Synonyms | HPC, L-HPC, KLUCEL, Hyprolose, Low-Substituted Hydroxypropyl Cellulose, Hydroxypropyl Cellulose (MW 80,000–1,250,000) |
| CB Number | CB0241870 |
| MDL Number | MFCD00132688 |
Physical & Chemical Properties
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Appearance: White to light cream powder
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Form: Powder
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Odor: Odorless
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Melting Point: 371.06 °C
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Density: 0.5 g/mL at 25 °C
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Refractive Index: 1.5600
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pH (20 g/L, 25 °C): 5.0–7.5
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pH Range: 5.0–8.5
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Viscosity: 3.0–6.0 mPa·s (2 %, H2O, 20 °C)
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Solubility: Soluble in water, methanol, ethanol, and other polar organic solvents
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Stability: Stable; incompatible with strong oxidizing agents; combustible
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Storage: Room temperature
Regulatory References
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FDA 21 CFR: 172.870; 73.1001
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FDA UNII Codes: Multiple entries depending on MW (e.g., 160000 WAMW, 650000 WAMW, 110000 WAMW)
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EPA Substance Registry: Cellulose, 2-hydroxypropyl ether (CAS 9004-64-2)
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Merck Index: 14,4841
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EWG Food Scores: 1
Applications
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Pharmaceuticals:
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Treatment of eye conditions (keratoconjunctivitis sicca, recurrent corneal erosions, neuroparalytic keratitis)
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Lubricant for artificial eyes
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Food & Cosmetics:
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Thickener, emulsion stabilizer, binder
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Biotechnology:
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Sieving matrix for DNA separation in capillary and microchip electrophoresis
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Cultural Heritage:
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Main ingredient of Cellugel, used in book conservation
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