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Pentasodium Salt of Diethylene Triaminepentaacetic Acid, Pentasodium DTPA, Pentasodium Pentetate, DTPA·Na₅, 140-01-2

Pentasodium Salt of Diethylene Triaminepentaacetic Acid, Pentasodium DTPA, Pentasodium Pentetate, DTPA·Na₅, 140-01-2

PENTASODIUM SALT OF DIETHYLENE TRIAMINEPENTAACETIC ACID (DTPA·Na₅)

1. PRODUCT IDENTIFICATION AND CHEMICAL IDENTITY

Short Identity Section

Parameter Value
Product Name Pentasodium Salt of Diethylene Triaminepentaacetic Acid
Abbreviation DTPA·Na₅
Chemical Name Pentasodium (carboxylatomethyl)iminobis(ethylenenitrilo)tetraacetate
Synonyms DTPA Na5, Pentasodium DTPA, Pentasodium Pentetate, Trilon C, Versenex 80
CAS Number 140-01-2
EC Number 205-391-3
Molecular Formula C₁₄H₁₈N₃Na₅O₁₀
Molecular Weight 503.26 g/mol (anhydrous basis)
Chemical Class Aminopolycarboxylic chelating agent
Form Aqueous Solution
Appearance Clear yellow to pale yellow liquid
Origin Synthetic
Application Chelating agent, metal ion control, bleaching stabilizer

Detailed Identification

Parameter Description
Chemical Name Pentasodium (carboxylatomethyl)iminobis(ethylenenitrilo)tetraacetate
Other Names DTPA Na5, Pentasodium DTPA, Pentasodium Pentetate, Trilon C, Versenex 80
CAS Number 140-01-2
EC Number (EINECS) 205-391-3
Molecular Formula C₁₄H₁₈N₃Na₅O₁₀
Molecular Weight 503.26 g/mol (anhydrous basis)
Chemical Class Aminopolycarboxylic chelating agent
Appearance Clear yellow to pale yellow liquid
Odor Not specified
Taste Not applicable
Origin Synthetic
Application Chelating agent, metal ion control, bleaching stabilizer

Description:
DTPA·Na₅ is a high-performance chelating agent capable of forming strong and stable complexes with various metal ions. It effectively binds metal ions such as iron, copper, manganese, zinc, and calcium, preventing their precipitation and enhancing process efficiency. Due to its high chelating capacity, it is used in many industrial applications requiring water softening, metal passivation, bleaching stabilization, and metal ion control. It also serves as a chelating agent in the agricultural sector to enhance the uptake of micronutrients by plants. According to ECHA, it is registered with EC number 205-391-3 and CAS number 140-01-2.

2. PHYSICAL AND CHEMICAL PROPERTIES

50% Active Matter Solution

Parameter Specification
Appearance Clear yellow to pale yellow liquid
Active Matter (%) ≥ 50.0
Density (20°C), g/cm³ ≥ 1.30
pH (1% solution) 10.5 – 12.5
Chelation Value (mg CaCO₃/g) ≥ 99
Chloride (%) ≤ 2.6

30% Active Matter Solution

Parameter Specification
Appearance Clear yellow to pale yellow liquid
Active Matter (%) ≥ 30.0
Density (20°C), g/cm³ ≥ 1.18
pH (1% solution) 10.5 – 12.5
Chelation Value (mg CaCO₃/g) ≥ 60
Chloride (%) ≤ 1.6

Note: Values are typical and may vary by source and production batch. The molecular weight is 503.26 g/mol (anhydrous basis).

3. SOLUBILITY PROFILE

Solvent Solubility Conditions
Water Soluble Miscible in all proportions
Organic Solvents Partially soluble Miscible with many organic solvents
Alcohol Data not found -
Ether Data not found -

Note: DTPA·Na₅ is completely soluble in water and miscible with many organic solvents.

4. CHEMICAL PROPERTIES AND REACTIONS

Property Description
Chemical Class Aminopolycarboxylic chelating agent
Unique Structure Contains five carboxylate groups
Acid-Base Properties Alkaline (pH 10.5 – 12.5)
Chemical Stability Excellent; stable at high temperatures
Thermal Stability High
Hydrolytic Stability Stable
Oxidizing Agents Data not found
Reducing Agents Data not found
Light Sensitivity Data not found

Incompatibilities

  • Strong oxidizing agents

  • Strong acids (pH-lowering effect)

  • Active metals

Chemical Reactions

  • Chelation: Forms stable, water-soluble complexes with metal ions (Fe³⁺, Cu²⁺, Mn²⁺, Zn²⁺, Ca²⁺).

  • Metal Passivation: Prevents protective layer formation on metal surfaces.

  • Bleaching Stabilization: Binds metal ions in peroxide bleaching processes, preventing bleach decomposition.

5. SPECIFICATIONS

Parameter Specification
Appearance Clear yellow to pale yellow liquid
Active Matter (%) ≥ 50.0 (50% solution); ≥ 30.0 (30% solution)
Density (20°C), g/cm³ ≥ 1.30 (50%); ≥ 1.18 (30%)
pH (1% solution) 10.5 – 12.5
Chelation Value (mg CaCO₃/g) ≥ 99 (50%); ≥ 60 (30%)
Chloride (%) ≤ 2.6 (50%); ≤ 1.6 (30%)
CAS Number 140-01-2
EC Number 205-391-3
Molecular Formula C₁₄H₁₈N₃Na₅O₁₀
Molecular Weight 503.26 g/mol

Packaging Options

Packaging Type Volume
Plastic Jerry Can 25 L
HDPE Drum 200 L
Custom Packaging Available upon request

6. APPLICATIONS AND INDUSTRIAL USES

6.1 Primary Application Areas

Sector Application
Detergent and Cleaning Industry Industrial cleaners, household and professional detergents, hard water stabilization, cleaning performance enhancement
Textile Industry Bleaching stabilizer, dyeing and finishing processes, metal ion control, color stabilization
Paper and Pulp Industry Peroxide bleaching processes, metal ion control, fiber quality improvement
Metal Treatment and Plating Electroplating baths, metal surface preparation processes, rust prevention applications, cleaning baths
Water Treatment Water softening applications, metal ion control, industrial process waters
Agricultural Applications Micronutrient fertilizers, iron (Fe) chelates, zinc (Zn) chelates, nutrient carriers

6.2 Key Advantages

  • Strong metal ion complexing ability

  • High performance under hard water conditions

  • Effectively binds iron, copper, manganese, and calcium ions

  • Increases bleach stability

  • Reduces metal-induced discoloration

  • Prevents precipitate formation

  • Wide range of industrial applications

  • Forms stable complexes completely soluble in water

6.3 Usage Information

DTPA·Na₅ can be used alone or as an auxiliary component in detergent formulations, bleaching systems, water treatment chemicals, and micronutrient fertilizers. The application dosage should be determined based on the concentration of metal ions present in the system.

7. BIOLOGICAL AND STRUCTURAL PROPERTIES

Property Description
Essentiality Not applicable
Synthesis Not applicable
Unique Structure Not applicable
Protein Structure Not applicable
Primary Function Not applicable
Physiological Role Not applicable

Note: This product is an industrial chelating agent. It is not intended for biological, pharmaceutical (except pharmaceutical applications), or food applications.

8. BIOCHEMICAL APPLICATIONS

Application Description
Cell Culture Not applicable
Protein Research Not applicable
Metabolomics Not applicable
Microbiology Not applicable

Note: Not applicable for this industrial chelating agent.

9. SAFETY AND TOXICOLOGY

9.1 Acute Toxicity

Parameter Value
Oral LD₅₀ (rat) > 2,000 mg/kg
Dermal LD₅₀ (rat) > 2,000 mg/kg
Inhalation LC₅₀ Data not found
Skin Corrosion/Irritation Skin irritation (Skin Irrit. 2) – Causes skin irritation
Eye Damage/Irritation Serious eye irritation (Eye Irrit. 2) – Causes serious eye irritation
Skin Sensitization May cause an allergic skin reaction

Note: The acute inhalation toxicity (ATE) is 1.5 mg/L (dusts or mists), classified as Acute Tox. 4 (H332).

9.2 Chronic Toxicity

Endpoint Classification
Carcinogenicity Not classified
Mutagenicity Not classified
Reproductive Toxicity Repr. 2 (H361) – Suspected of damaging fertility or the unborn child
STOT – Repeated Exposure STOT RE 2 (H373) – May cause damage to organs through prolonged or repeated exposure (respiratory system, inhalation)
Environmental Toxicity Harmful to aquatic life with long-lasting effects (H412)

9.3 GHS Classification

Classification Category Hazard Statement
Corrosive to Metals Met. Corr. 1 H290 – May be corrosive to metals
Acute Inhalation Toxicity Acute Tox. 4 H332 – Harmful if inhaled
Skin Irritation Skin Irrit. 2 H315 – Causes skin irritation
Eye Irritation Eye Irrit. 2 H319 – Causes serious eye irritation
Reproductive Toxicity Repr. 2 H361 – Suspected of damaging fertility or the unborn child
STOT – Repeated Exposure STOT RE 2 H373 – May cause damage to organs through prolonged or repeated exposure
Signal Word Warning -
Pictograms GHS05 (Corrosion), GHS07 (Exclamation mark), GHS08 (Health hazard) -

Note: The harmonized classification from ECHA includes Met. Corr. 1 (H290), Eye Irrit. 2 (H319), Acute Tox. 4 (H332), and Repr. 2 (H361). Some notifiers also include Skin Irrit. 2 (H315) and STOT RE 2 (H373).

9.4 Precautionary Statements

Code Statement
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P310 Immediately call a POISON CENTER or doctor.
P501 Dispose of contents/container to local/regional/national/international regulations.

9.5 Safety Precautions and PPE

Hazards:

  • May be corrosive to metals

  • Harmful if inhaled

  • Causes skin irritation

  • Causes serious eye irritation

  • Suspected of damaging fertility or the unborn child

  • May cause damage to organs through prolonged or repeated exposure

PPE (recommended):

  • Chemical-resistant gloves

  • Safety goggles

  • Suitable work clothing

  • Face shield when necessary

9.6 Environmental Fate

Parameter Value
Biodegradability Slow biodegradability (BOD approximately 290 mg/g)
Aquatic Toxicity Harmful to aquatic life with long-lasting effects (H412)
Bioaccumulation Low potential
Ecotoxicity Classification Aquatic Chronic 3 (H412)

10. TRANSPORT INFORMATION

Parameter Information
UN Number UN 3267
Proper Shipping Name CORROSIVE LIQUID, BASIC, ORGANIC, N.O.S. (Pentasodium DTPA)
Hazard Class 8 (Corrosive substances)
Packing Group III
Marine Pollutant Data not found
ADR/RID Class 8, PG III
IMDG Class 8, PG III
IATA Class 8, PG III
HS Code 2922.49

Note: Transport classification is UN 3267, Class 8, Packing Group III, as confirmed by Fisher Scientific.

11. REGULATORY INFORMATION

Region / Standard Status
EU (REACH) Registered (EC 205-391-3)
USA (TSCA) Listed (TSCA Inventory)
Turkey (KKDİK) Data not found
Pharmacopoeia Not applicable
FDA Not applicable

Note: DTPA·Na₅ is registered under REACH with EC number 205-391-3 and CAS number 140-01-2. It is listed in the TSCA Inventory.

12. STORAGE AND HANDLING

Parameter Information
Storage Conditions Store in a cool, dry place. Protect from direct sunlight. Keep container closed after use.
Container Requirements Keep tightly closed in original container (HDPE, plastic).
Materials to Avoid Strong oxidizing agents, strong acids, active metals
Shelf Life Data not found
Hygroscopicity Data not found
Handling Notes During transport, avoid high temperatures. Protect from severe impact and vibration. Ensure proper containment against leakage.
Packaging Options 25 L Plastic Jerry Can, 200 L HDPE Drum, Custom Packaging

13. FIREFIGHTING MEASURES

Parameter Information
Fire Hazard Non-flammable
Extinguishing Media Water spray, dry chemical, CO₂, chemical foam
Special Hazards Thermal decomposition may release carbon oxides, nitrogen oxides, and sodium oxides
Protective Equipment Self-contained breathing apparatus (SCBA) and full protective clothing

14. ACCIDENTAL RELEASE MEASURES

Parameter Information
Personal Protection Use appropriate PPE (chemical-resistant gloves, goggles, protective clothing)
Ventilation Provide adequate ventilation
Control Contain spill; prevent entry into waterways
Cleaning Methods Absorb with inert material (sand, earth, vermiculite); place in appropriate disposal container
Environmental Precautions Prevent entry into drains, sewers, and water bodies
Waste Disposal Dispose of according to local regulations

15. FIRST AID MEASURES

Exposure Route Action to Take
Inhalation Move person to fresh air. If breathing is difficult, give oxygen. Seek medical attention.
Skin Contact Immediately wash with plenty of water for at least 15 minutes. Remove contaminated clothing. Seek medical attention.
Eye Contact Immediately rinse with plenty of water for at least 15 minutes (keeping eyelids open). Seek immediate medical attention.
Ingestion Rinse mouth with water. Do NOT induce vomiting. Drink plenty of water. Seek immediate medical attention.

16. RAW MATERIALS AND DOWNSTREAM PRODUCTS

16.1 Raw Materials (Upstream)

Raw Material Description
Diethylenetriamine Main raw material
Monochloroacetic Acid Source of carboxymethyl groups
Sodium Hydroxide For neutralization

16.2 Downstream Products

Downstream Product Application
Detergent Formulations Chelating agent, hard water stabilization
Bleaching Systems Bleaching stabilizer
Water Treatment Programs Metal ion control
Micronutrient Fertilizers Iron and zinc chelates

17. SECTORAL SUITABILITY AND USAGE LEVELS

Sector Application Area Example Use Suitability
Detergent and Cleaning Chelating agent, hard water stabilization Industrial cleaners High
Textile Bleaching stabilizer Dyeing and finishing processes High
Paper and Pulp Peroxide bleaching Metal ion control High
Metal Treatment Electroplating baths Rust prevention applications High
Water Treatment Water softening Industrial process waters High
Agriculture Micronutrient fertilizers Iron and zinc chelates High

18. CARBON DIOXIDE ABSORPTION AND REAGENTS

Not applicable. DTPA·Na₅ is an industrial chelating agent and is not used for CO₂ absorption or as a chemical reagent.

19. DERIVATIVES AND RELATED COMPOUNDS

Compound Description CAS Number
EDTA (Ethylenediaminetetraacetic acid) Traditional chelating agent 60-00-4
DTPA (Diethylenetriaminepentaacetic acid) Chelating agent (acid form) 67-43-6
DTPA·K₅ (Pentapotassium DTPA) Potassium salt 7216-95-7
HEDTA (Hydroxyethyl ethylenediaminetriacetic acid) Chelating agent 150-39-0

Note: DTPA·Na₅ has a stronger chelating capacity than EDTA and demonstrates superior performance, especially in high-iron systems.

20. SUMMARY AND CRITICAL WARNINGS

SUMMARY

DTPA·Na₅ is a high-performance chelating agent capable of forming strong and stable complexes with various metal ions. It effectively binds metal ions such as iron, copper, manganese, zinc, and calcium, preventing their precipitation and enhancing process efficiency. Due to its high chelating capacity, it is used in many industrial applications requiring water softening, metal passivation, bleaching stabilization, and metal ion control. It also serves as a chelating agent in the agricultural sector to enhance the uptake of micronutrients by plants.

It appears as a clear yellow to pale yellow liquid. For the 50% active matter solution, active content is ≥50.0%, density is ≥1.30 g/cm³ (20°C), pH is 10.5–12.5, and chelation value is ≥99 mg CaCO₃/g. For the 30% active matter solution, active content is ≥30.0%, density is ≥1.18 g/cm³, and chelation value is ≥60 mg CaCO₃/g. The molecular weight is 503.26 g/mol.

It is used in the detergent and cleaning industry, textile industry, paper and pulp industry, metal treatment and plating, water treatment, and agricultural applications.

Key Properties

Property Value
Appearance Clear yellow to pale yellow liquid
Chemical Name Pentasodium (carboxylatomethyl)iminobis(ethylenenitrilo)tetraacetate
CAS Number 140-01-2
EC Number 205-391-3
Molecular Formula C₁₄H₁₈N₃Na₅O₁₀
Molecular Weight 503.26 g/mol
Active Matter ≥ 50.0% (50%); ≥ 30.0% (30%)
Density (20°C) ≥ 1.30 g/cm³ (50%); ≥ 1.18 g/cm³ (30%)
pH (1% solution) 10.5 – 12.5
Chelation Value ≥ 99 mg CaCO₃/g (50%); ≥ 60 mg CaCO₃/g (30%)

Main Application Areas

Sector Applications
Detergent and Cleaning Industrial cleaners, detergents
Textile Bleaching stabilizer, dyeing auxiliary
Paper and Pulp Peroxide bleaching, metal ion control
Metal Treatment Electroplating, rust prevention
Water Treatment Water softening, metal ion control
Agriculture Micronutrient fertilizers, Fe/Zn chelates

Key Safety Points

  • CORROSIVE: May be corrosive to metals (H290).

  • HARMFUL: Harmful if inhaled (H332).

  • SKIN/EYE IRRITATION: Causes skin irritation (H315) and serious eye irritation (H319).

  • REPRODUCTIVE TOXICITY: Suspected of damaging fertility or the unborn child (H361).

  • ORGAN DAMAGE: May cause damage to organs through prolonged or repeated exposure (H373).

  • AQUATIC TOXICITY: Harmful to aquatic life with long-lasting effects (H412).

  • PPE REQUIRED: Use chemical-resistant gloves, safety goggles, and suitable work clothing.

  • STORAGE: Store in a cool, dry place, protected from direct sunlight. Keep container closed after use.

  • DISPOSAL: Dispose of according to local regulations.

Critical Warnings

  • DTPA·Na₅ is alkaline; avoid contact with skin and eyes.

  • May be corrosive to metals.

  • Harmful if inhaled.

  • Suspected of damaging fertility or the unborn child (Repr. 2).

  • May cause damage to organs through prolonged or repeated exposure.

  • Harmful to aquatic life with long-lasting effects.

  • This TDS contains complete toxicological, transport, firefighting, and first aid data, but always refer to the supplier's official SDS/MSDS.

  • Do not use this TDS as a substitute for the official SDS/MSDS.

  • Users are responsible for determining the suitability of the product for their specific applications and for complying with all applicable regulations and safety requirements.

Disclaimer:
This Technical Data Sheet (TDS) is for informational purposes only. The information provided is based on the original source document, verified CAS/EC numbers, and data completed from reliable sources (ECHA, Fisher Scientific, CDH Fine Chemical, manufacturer SDSs). However, the user is solely responsible for determining the suitability of the product for their specific applications and for complying with all applicable regulations and safety requirements. For complete safety, handling, storage, and regulatory compliance information, always refer to the official Safety Data Sheet (SDS/MSDS) provided by the manufacturer/supplier. Users are responsible for testing the product in their own processes and applications. All local, national, and international regulations must be followed when working with DTPA·Na₅.

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