We unleash your business potential by maximize the business innovation.
Send EmailC12-14 Alkyl Dimethyl Amine Oxide, Lauramine Oxide, Lauryl Dimethyl Amine Oxide, Myristamine Oxide, Myristyl Dimethyl Amine Oxide, 308062-28-4, 1643-20-5, 3332-27-2
C12-14 ALKYL DIMETHYL AMINE OXIDE
1. PRODUCT IDENTIFICATION AND CHEMICAL IDENTITY
Short Identity Section
| Parameter | Value |
|---|---|
| Product Name | C12-14 Alkyl Dimethyl Amine Oxide |
| Chemical Name | Amines, C12-14 (even numbered)-alkyldimethyl, N-oxides |
| Other Names | C12-14 AO, C12-14 Amine Oxide, Lauramine Oxide / Myristamine Oxide blend, N,N-Dimethylalkylamine N-oxide (C12-14) |
| CAS Number | 308062-28-4 |
| EC Number | 931-292-6 |
| Molecular Formula | R(CH₃)₂N→O (R = C₁₂H₂₅ and C₁₄H₂₉) |
| Chemical Class | Amine oxide (non-ionic to cationic surfactant) |
| Appearance | Colorless to pale yellow clear liquid or powder |
| Odor | Mild, characteristic amine oxide odor |
| Origin | Synthetic |
| Application | Detergents, personal care, industrial cleaning |
Related CAS Numbers and Isomers
| Component | CAS Number | Chemical Name |
|---|---|---|
| C12-14 Alkyl Dimethyl Amine Oxide | 308062-28-4 | Amines, C12-14 (even numbered)-alkyldimethyl, N-oxides |
| Lauramine Oxide (Lauryl Dimethyl Amine Oxide) | 1643-20-5 | 1-Dodecanamine, N,N-dimethyl-, N-oxide |
| Myristamine Oxide (Myristyl Dimethyl Amine Oxide) | 3332-27-2 | 1-Tetradecanamine, N,N-dimethyl-, N-oxide |
Detailed Identification
| Parameter | Description |
|---|---|
| Chemical Name | Amines, C12-14 (even numbered)-alkyldimethyl, N-oxides |
| Other Names | C12-14 Alkyl Dimethyl Amine Oxide, Lauramine Oxide / Myristamine Oxide blend, C12-14 Amine Oxide, C12-14 AO |
| CAS Number | 308062-28-4 |
| EC Number (EINECS) | 931-292-6 |
| Molecular Formula | R(CH₃)₂N→O (where R = C₁₂H₂₅ and C₁₄H₂₉, even-numbered carbon chains) |
| Molecular Weight | Variable (depends on chain distribution) |
| Chemical Class | Amine oxide (non-ionic to cationic surfactant) |
| Appearance | Colorless to pale yellow clear liquid or powder (concentration dependent) |
| Physical State (20°C) | Liquid (30% solution) or solid (anhydrous powder) |
| Odor | Mild, characteristic amine oxide odor |
| Taste | Not applicable |
| Origin | Synthetic |
| Application | Detergents, personal care, industrial cleaning |
Explanation:
C12-14 Alkyl Dimethyl Amine Oxide is a blend of even-numbered carbon chain (C12 and C14) alkyl dimethyl amine oxides. The amine oxide group is highly polar and can function as both a hydrogen bond acceptor and donor. It is a versatile surfactant that can exhibit cationic, non-ionic, or zwitterionic character depending on pH. It is registered in the ECHA database under the name "Amines, C12-14 (even numbered)-alkyldimethyl, N-oxides" with EC number 931-292-6.
2. PHYSICAL AND CHEMICAL PROPERTIES
| Property | Value |
|---|---|
| Density (23°C) | 0.716 g/cm³ (anhydrous); ~1.0 g/cm³ (30% solution) |
| Vapor Pressure (25°C) | 0 – 0 Pa (negligible) |
| Melting Point | Variable (depends on concentration and chain distribution) |
| Flash Point | >100°C (non-flammable for aqueous solutions) |
| pH (10% aqueous solution) | 6.5 – 8.5 (typically neutral to slightly alkaline) |
| Water Solubility | Soluble (forms clear solutions) |
| Solubility in Organic Solvents | Soluble in alcohols, ethers, ketones; partially soluble in hydrocarbons |
| Cloud Point | Typically >100°C |
| Surface Tension (0.1% solution) | ~30 – 35 mN/m |
| Foam Height (Ross-Miles) | High (excellent foam booster) |
| Krafft Point | <0°C (remains soluble in cold water) |
| Viscosity (25°C, 30% solution) | 20 – 100 cP |
| Color (APHA) | ≤ 100 |
pH-Dependent Properties
| pH Range | Behavior |
|---|---|
| pH < 3 (acidic) | Cationic (protonated form) – behaves as cationic surfactant |
| pH 4 – 8 (neutral) | Zwitterionic / non-ionic (predominantly amine oxide form) |
| pH > 8 (alkaline) | Non-ionic (stable amine oxide) |
| pH > 10 | May slowly degrade |
3. SOLUBILITY PROFILE
| Solvent | Solubility | Conditions |
|---|---|---|
| Water | Soluble | Clear solution |
| Alcohol | Soluble | - |
| Ether | Soluble | - |
| Ketone | Soluble | - |
| Hydrocarbon | Partially soluble | - |
4. CHEMICAL PROPERTIES AND REACTIONS
| Property | Description |
|---|---|
| Chemical Class | Amine oxide (tertiary amine oxide) |
| Unique Structure | R–N⁺(CH₃)₂–O⁻ (amine oxide) |
| Acid-Base Properties | Amphoteric; cationic/non-ionic depending on pH |
| Stability at Neutral pH | Excellent |
| Thermal Stability | Stable up to 50°C; degrades above 80°C |
| Hydrolytic Stability | Stable under neutral and alkaline conditions; may degrade in strong acids |
| Oxidizing Agents | Compatible with most oxidizing agents (peroxides, hypochlorite) |
| Reducing Agents | Can be reduced to tertiary amine |
| Light Sensitivity | Stable (no significant degradation) |
Decomposition Products
| Condition | Products |
|---|---|
| Strong acid (pH <2) | Protonated amine oxide (reversible) |
| Strong acid + heat | Tertiary amine + water |
| Strong base (>pH 12) | No decomposition (stable) |
| High temperature (>150°C) | Tertiary amine + oxygen |
Incompatibilities
-
Strong reducing agents (can reduce amine oxide to tertiary amine)
-
Strong mineral acids (low pH causes protonation but not degradation; extreme pH with heat can cause degradation)
-
Strong oxidizing agents (generally compatible but may cause exothermic reaction at high concentrations)
Chemical Reactions
-
Protonation (pH <3): R(CH₃)₂N→O + H⁺ ⇌ R(CH₃)₂N⁺–OH (cationic form)
-
Reduction: Reduced to tertiary amine by strong reducing agents
-
Oxidation: Exothermic reaction with high concentrations of oxidizing agents
-
Hydrolysis: Stable under neutral and alkaline conditions; reversible protonation in strong acids
5. SPECIFICATIONS
30% Aqueous Solution Specifications
| Parameter | Specification | Test Method |
|---|---|---|
| Appearance | Clear to slightly hazy, colorless to pale yellow liquid | Visual |
| Active Content (amine oxide, w/w) | 29.0 – 31.0% | Titration |
| Free Amine (tertiary amine) | ≤ 0.5% | Titration |
| Residual Hydrogen Peroxide | ≤ 0.05% | Titration |
| pH (as is) | 6.5 – 8.5 | pH meter |
| Density (20°C) | ~1.0 g/cm³ | Hydrometer |
| Color (APHA) | ≤ 100 | Visual |
| Viscosity (25°C) | 20 – 100 cP | Brookfield |
| Iron (Fe) | ≤ 5 ppm | ICP-OES |
Powder / Anhydrous Form Specifications
| Parameter | Specification |
|---|---|
| Appearance | White to off-white powder |
| Active Content | ≥ 95% |
| Free Amine | ≤ 2.0% |
| Moisture | ≤ 5% |
Available Product Grades
| Grade | Active Content | Form | Applications |
|---|---|---|---|
| 30% Aqueous Solution | 29 – 31% | Clear to pale yellow liquid | Detergents, personal care, industrial cleaning |
| 50% Aqueous Solution | 49 – 51% | Viscous liquid | Industrial applications, concentrates |
| Anhydrous Powder | ≥ 95% | White to off-white powder | Specialty formulations, solid products |
Packaging Options
| Packaging Type | Weight |
|---|---|
| Drum (HDPE) | 200 kg |
| IBC Container | On request |
| Bulk | On request |
6. APPLICATIONS AND INDUSTRIAL USES
6.1 Detergents and Cleaning Products
| Application | Function | Typical Concentration |
|---|---|---|
| Laundry detergents | Foam booster, stabilizer, viscosity regulator | 1 – 5% |
| Dishwashing liquids | Foam booster, grease emulsifier | 2 – 8% |
| Hand soaps | Foam booster, mildness enhancer | 1 – 5% |
| Hard surface cleaners | Wetting agent, soil suspension | 0.5 – 3% |
| Industrial cleaners | Emulsifier, detergent | 1 – 10% |
| Car wash shampoos | Foam booster, lubricant | 1 – 5% |
Benefits: Excellent foam boosting and stabilization; mild to skin (reduces irritation of anionic surfactants); good lime soap dispersant; viscosity builder in certain formulations; biodegradable.
6.2 Personal Care and Cosmetics
| Application | Function | Typical Concentration |
|---|---|---|
| Shampoos | Foam booster, mildness enhancer, conditioning | 1 – 5% |
| Shower gels | Foam booster, viscosity builder | 1 – 5% |
| Facial cleansers | Mild surfactant, foam booster | 0.5 – 3% |
| Bath products | Foam booster, skin feel enhancer | 1 – 4% |
| Hair conditioners | Antistatic agent, conditioning | 0.5 – 2% |
| Baby shampoos | Mild cleansing, low irritation | 1 – 5% |
6.3 Shampoo Formulation (Example)
| Ingredient | % w/w |
|---|---|
| SLES (70%) | 10.0 |
| C12-14 Amine Oxide | 2.0 |
| Cocamidopropyl Betaine | 3.0 |
| PEG-150 Distearate | 0.5 |
| Preservative | q.s. |
| Water | q.s. to 100 |
6.4 Dishwashing Liquid Formulation (Example)
| Ingredient | % w/w |
|---|---|
| SLES (70%) | 15.0 |
| C12-14 Amine Oxide | 5.0 |
| Cocamide DEA | 2.0 |
| Sodium chloride | 1.0 |
| Fragrance | 0.5 |
| Water | q.s. to 100 |
6.5 Other Industrial Applications
| Industry | Application | Function |
|---|---|---|
| Textiles | Fiber lubricant, antistatic agent, wetting agent, dyeing assistant | Reduces friction, reduces static charge, improves penetration |
| Oil & Gas | Corrosion inhibitor, biocide adjuvant, emulsifier, foaming agent | Forms protective film, enhances efficacy |
| Paints & Coatings | Pigment dispersant, wetting agent | Stabilizes suspensions, improves wetting |
| Metalworking | Emulsifier, corrosion inhibitor, wetting agent | Stabilizes emulsions, improves cooling and lubrication |
| Agriculture | Adjuvant, emulsifier, wetting agent | Improves wetting and penetration |
7. BIOLOGICAL AND STRUCTURAL PROPERTIES
| Property | Description |
|---|---|
| Essentiality | Not applicable |
| Synthesis | Not applicable |
| Unique Structure | Not applicable |
| Protein Structure | Not applicable |
| Primary Function | Not applicable |
| Physiological Role | Not applicable |
Note: This product is an industrial surfactant. It is not intended for biological, pharmaceutical (except pharmaceutical applications), or food applications.
8. BIOCHEMICAL APPLICATIONS
| Application | Description |
|---|---|
| Cell Culture | Not applicable |
| Protein Research | Not applicable |
| Metabolomics | Not applicable |
| Microbiology | Not applicable |
Note: Not applicable for this industrial surfactant.
9. SAFETY AND TOXICOLOGY
9.1 Acute Toxicity
| Parameter | Value |
|---|---|
| Oral LD₅₀ (rat) | 2,000 – 5,000 mg/kg (low to moderate toxicity) |
| Dermal LD₅₀ (rabbit) | >2,000 mg/kg |
| Skin Irritation | Mild irritant |
| Eye Irritation | Moderate to severe irritant |
| Skin Sensitization | Generally not sensitizing |
| Inhalation | Not expected to be hazardous (low vapor pressure) |
9.2 Chronic Toxicity
| Endpoint | Classification |
|---|---|
| Carcinogenicity | Not classified |
| Mutagenicity | Negative |
| Reproductive Toxicity | Not classified |
| Environmental Toxicity | Moderate (algae and aquatic invertebrates sensitive) |
9.3 GHS Classification
| Classification | Category |
|---|---|
| Signal Word | Warning (for concentrated product) |
| Hazard Statements | H315 – Causes skin irritation; H319 – Causes serious eye irritation; H400 – Very toxic to aquatic life |
| Precautionary Statements | P264, P280, P302+P352, P305+P351+P338, P332+P313, P337+P313, P273, P391, P501 |
9.4 Safety Precautions and PPE
Hazards:
-
Causes eye irritation (concentrated product)
-
May cause skin irritation
-
Toxic to aquatic life – avoid environmental release
PPE (recommended):
-
Chemical-resistant gloves (nitrile or neoprene)
-
Safety goggles (EN 166) or chemical splash goggles
-
Protective clothing (for industrial handling)
9.5 Environmental Fate
| Parameter | Value |
|---|---|
| Biodegradability | Readily biodegradable (OECD 301) |
| Aquatic Toxicity (fish, LC₅₀, 96h) | 1 – 10 mg/L (moderate to high) |
| Daphnia magna (EC₅₀, 48h) | 1 – 10 mg/L |
| Algae (EC₅₀, 72h) | 0.5 – 5 mg/L (sensitive) |
| Bioaccumulation | Low potential |
| Ecotoxicity Classification | H400 (Very toxic to aquatic life) |
Note: Amine oxides are known to be toxic to aquatic organisms, especially algae. Avoid direct discharge into water bodies.
10. TRANSPORT INFORMATION
| Regulation | Classification |
|---|---|
| UN Number | Typically not regulated |
| ADR/RID | Not classified as dangerous goods |
| IMDG | Not regulated |
| IATA | Not regulated |
| Proper Shipping Name | Amine oxide solution (non-hazardous for most concentrations) |
11. REGULATORY INFORMATION
| Regulation | Status |
|---|---|
| REACH (EU) | Registered |
| TSCA (USA) | Listed |
| EU Detergents Regulation (EC 648/2004) | Permitted as surfactant |
| EU Cosmetic Regulation (EC 1223/2009) | Permitted (up to 5% in leave-on, up to 30% in rinse-off) |
| FDA (USA) | Permitted for certain applications |
| Turkey (KKDİK) | Registered under KKDİK |
12. STORAGE AND HANDLING
| Parameter | Requirement |
|---|---|
| Temperature | 5 – 40°C (room temperature) |
| Container | Keep tightly closed in original container (HDPE, stainless steel) |
| Protect From | Freezing (may gel upon freezing; thaw and mix before use), strong acids, strong reducing agents |
| Environment | Cool, dry, well-ventilated area |
| Shelf Life (closed) | 12 – 24 months |
| Shelf Life (opened) | 6 – 12 months |
Packaging: 200 kg drum
Note: Amine oxide solutions may gel upon freezing, but revert to liquid upon warming with gentle mixing.
12.1 Transport Precautions
| Parameter | Recommendation |
|---|---|
| Ventilation | Adequate ventilation |
| Personal Hygiene | Wash hands after handling |
| Spill Response | Contain spill; prevent entry into waterways |
13. FIREFIGHTING MEASURES
| Parameter | Information |
|---|---|
| Fire Hazard | Non-flammable for aqueous solutions |
| Extinguishing Media | Water spray, CO₂, dry chemical powder |
| Special Hazards | Thermal decomposition may release tertiary amine and oxygen |
| Protective Equipment | Standard protective equipment |
14. ACCIDENTAL RELEASE MEASURES
| Parameter | Information |
|---|---|
| Personal Protection | Use appropriate PPE (gloves, goggles, protective clothing) |
| Ventilation | Provide adequate ventilation |
| Control | Contain spill; prevent entry into waterways |
| Cleaning Methods | Absorb with inert material; place in appropriate disposal container |
| Environmental Precautions | Prevent entry into drains, sewers, and water bodies |
| Waste Disposal | Dispose of according to local regulations |
15. FIRST AID MEASURES
| Exposure Route | Action to Take |
|---|---|
| Eye Contact | Rinse with water for 15 minutes; remove contact lenses; seek medical attention if irritation persists |
| Skin Contact | Wash with soap and water |
| Inhalation | Move to fresh air (not a likely route of exposure) |
| Ingestion | Rinse mouth; DO NOT induce vomiting; drink water; seek medical attention if large amount swallowed |
16. RAW MATERIALS AND DOWNSTREAM PRODUCTS
16.1 Raw Materials (Upstream)
| Raw Material | Description |
|---|---|
| C12-14 Alkyl Dimethyl Tertiary Amine | Main raw material |
| Hydrogen Peroxide (H₂O₂) | Oxidizing agent |
16.2 Downstream Products
| Downstream Product | Application |
|---|---|
| Detergents | Laundry, dishwashing, surface cleaners |
| Personal Care Products | Shampoos, shower gels, facial cleansers |
| Industrial Cleaners | Hard surface, metalworking, textiles |
16.3 Commercial Products
| Commercial Product Name | Content | CAS Number |
|---|---|---|
| Lanol MAO 25 | Myristamine Oxide | 3332-27-2 |
| Lanol MCO | C12-14 Alkyl Dimethyl Amine Oxide | 308062-28-4 |
17. SECTORAL SUITABILITY AND USAGE LEVELS
| Sector | Application Area | Example Use | Suitability |
|---|---|---|---|
| Detergents | Foam booster, viscosity regulator | Laundry detergents, dishwashing liquids | High |
| Personal Care | Foam booster, mildness enhancer | Shampoos, shower gels | High |
| Industrial Cleaning | Emulsifier, wetting agent | Hard surface cleaners | High |
| Textiles | Antistatic, wetting agent | Fiber processing | High |
| Oil & Gas | Corrosion inhibitor, emulsifier | Drilling fluids | Moderate |
| Paints & Coatings | Pigment dispersant | Paint formulations | Moderate |
| Agriculture | Adjuvant | Pesticide formulations | Moderate |
18. CARBON DIOXIDE ABSORPTION AND REAGENTS
Not applicable. C12-14 Alkyl Dimethyl Amine Oxide is an industrial surfactant and is not used for CO₂ absorption or as a chemical reagent.
19. DERIVATIVES AND RELATED COMPOUNDS
| Compound | Description | CAS Number |
|---|---|---|
| Lauramine Oxide (Lauryl Dimethyl Amine Oxide) | C12 chain amine oxide; common trade names: Aromox C/12, Barlox 12, Chemoxide CAW, Empigen OB, Mackamine CAO, Schercamox C-AA, Tomamine AO-14-2 | 1643-20-5 |
| Myristamine Oxide (Myristyl Dimethyl Amine Oxide) | C14 chain amine oxide; common trade names: AMMONYX MO, Euroxide MAO, EMPIGEN OH 25, Lanol MAO 25 | 3332-27-2 |
| C12-14 Alkyl Dimethyl Amine Oxide | C12-14 blend; trade name: Lanol MCO | 308062-28-4 |
20. SUMMARY AND CRITICAL WARNINGS
SUMMARY
C12-14 Alkyl Dimethyl Amine Oxide is a blend of even-numbered carbon chain (C12 and C14) alkyl dimethyl amine oxides. The amine oxide group is highly polar and can exhibit cationic, non-ionic, or zwitterionic character depending on pH. It is a versatile surfactant widely used in detergents, personal care, and industrial cleaning applications due to its excellent foam boosting and stabilization, mildness to skin, good lime soap dispersing properties, and biodegradability.
It appears as a colorless to pale yellow clear liquid or powder. Its density is 0.716 g/cm³ (anhydrous) or ~1.0 g/cm³ (30% solution), pH is 6.5 – 8.5. It is soluble in water. It is toxic to aquatic life (H400).
Key Properties
| Property | Value |
|---|---|
| Appearance | Colorless to pale yellow clear liquid |
| Chemical Name | Amines, C12-14 (even numbered)-alkyldimethyl, N-oxides |
| CAS Number | 308062-28-4 |
| EC Number | 931-292-6 |
| Density (23°C) | 0.716 g/cm³ (anhydrous); ~1.0 g/cm³ (30% solution) |
| Active Content (typical) | 30% or 50% (liquid); ≥95% (powder) |
| pH (10% solution) | 6.5 – 8.5 |
| Water Solubility | Soluble |
| Foaming | Excellent |
| Biodegradability | Readily biodegradable |
| Aquatic Toxicity | Very toxic to aquatic life (H400) |
| GHS Signal Word | Warning |
| Hazard Statements | H315, H319, H400 |
Main Application Areas
| Sector | Applications |
|---|---|
| Detergents | Laundry detergents, dishwashing liquids, hand soaps |
| Personal Care | Shampoos, shower gels, facial cleansers |
| Industrial Cleaning | Hard surface cleaners, metalworking fluids |
| Textiles | Antistatic agent, wetting agent, dyeing assistant |
| Oil & Gas | Corrosion inhibitor, emulsifier |
Key Safety Points
-
EYE IRRITATION: Causes moderate to severe eye irritation (H319).
-
SKIN IRRITATION: Causes mild skin irritation (H315).
-
AQUATIC TOXICITY: Very toxic to aquatic life (H400). Avoid environmental release.
-
PPE REQUIRED: Use chemical-resistant gloves, safety goggles, and protective clothing.
-
STORAGE: Store at 5 – 40°C, tightly closed in original container. Protect from freezing.
-
DISPOSAL: Dispose of according to local regulations.
Critical Warnings
-
C12-14 Alkyl Dimethyl Amine Oxide is a blend of even-numbered carbon chain (C12, C14) amine oxides; composition may vary by production source.
-
May cause eye and skin irritation. Toxic to aquatic life.
-
This TDS contains complete toxicological, transport, firefighting, and first aid data, but always refer to the supplier’s official SDS/MSDS.
-
Do not use this TDS as a substitute for the official SDS/MSDS.
-
Users are responsible for determining the suitability of the product for their specific applications and for complying with all applicable regulations and safety requirements.
Disclaimer:
This Technical Data Sheet (TDS) is for informational purposes only. The information provided is based on the original source document, verified CAS numbers, and data completed from reliable sources (ECHA, manufacturer SDSs). However, the user is solely responsible for determining the suitability of the product for their specific applications and for complying with all applicable regulations and safety requirements. For complete safety, handling, storage, and regulatory compliance information, always refer to the official Safety Data Sheet (SDS/MSDS) provided by the manufacturer/supplier. Users are responsible for testing the product in their own processes and applications. All local, national, and international regulations must be followed when working with C12-14 Alkyl Dimethyl Amine Oxide.
